HitPredict

Interactor 1: PKHG3 (A1L390)
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene: PLEKHG3

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGEF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1219 Hs			1 205
+	Hs
		50617 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		50582 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		50580 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		50572 PKHG3_HUMAN (1-1219): 0: 955: 100.00		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		50573 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		50554 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		50571 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		50579 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		50546 PKHG3_HUMAN (1-1219): 0: 955: 100.00		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		564737 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		925727 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		894583 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		548678 VAV_HUMAN (3-587): 4.05e-114: 378: 18.38		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		548671 VAV_HUMAN (3-587): 4.05e-114: 378: 18.38		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		548672 VAV_HUMAN (3-587): 4.05e-114: 378: 18.38		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		925497 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		156394 RGRF2_HUMAN (12-758): 1.58e-106: 366: 13.29		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		900768 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		156395 RGRF2_HUMAN (12-758): 1.58e-106: 366: 13.29		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		915884 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51