HitPredict

Interactor 1: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38280479, 38223760
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030054 - cell junction GO:0065003 - protein-containing complex assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 504
+	Hs
		505678 EPB41_HUMAN (1-864): 0: 781: 100.00		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		505658 EPB41_HUMAN (1-864): 0: 781: 100.00		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		125188 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		1087931 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		808660 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		547209 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		546968 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		719588 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		719410 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		546967 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		547208 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		719609 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		299270 FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		1087910 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		1087899 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18
+	Hs
		719536 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		204630 E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		1336123 E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		204697 E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27
+	Hs
		1220100 E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67		KIBRA_HUMAN (167-309): 1.03e-35: 144: 27.27