HitPredict

Interactor 1: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Interactor 2: ICLN (P54105)
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)
Gene: CLNS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 35271311
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 864 Hs			1 237
+	Hs
		867467 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		299251 FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		867438 FRMD7_HUMAN (210-805): 9.82e-128: 402: 26.07		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		640225 PTN3_HUMAN (183-618): 3.39e-117: 380: 29.36		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		204636 E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		867491 E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00
+	Hs
		46554 A0A2R8Y783_HUMAN (714-760): 1.88e-09: 62: 72.00		ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00