HitPredict

Interactor 1: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.718

Property	Details
Experiments	33961781, 35271311, 36931259, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 247
+	Hs
		505612 EPB41_HUMAN (1-864): 0: 781: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		505625 EPB41_HUMAN (1-864): 0: 781: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		505557 EPB41_HUMAN (1-864): 0: 781: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		905141 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982526 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		910025 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		905110 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982496 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		663970 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		663969 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		683735 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		663976 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		647300 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683710 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927524 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		684340 E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		647274 E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		663962 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		663973 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646653 PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33