HitPredict

Interactor 1: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 400
+	Hs
		505580 EPB41_HUMAN (1-864): 0: 781: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		505658 EPB41_HUMAN (1-864): 0: 781: 100.00		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		547208 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		719609 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		808660 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		546968 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		719410 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1087931 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		547209 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		299270 FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		125188 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1087910 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1087899 PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32		WWC2_HUMAN (121-264): 2.83e-43: 163: 15.97
+	Hs
		719536 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		719615 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		SAV1_HUMAN (2-252): 3.57e-48: 169: 15.89
+	Hs
		546967 EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		719588 MERL_HUMAN (195-763): 8.67e-121: 380: 19.69		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		204630 E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		204697 E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1220100 E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88