Interactor 1: UMPS (P11172)
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)]
Gene: UMPS
Interactor 2: UMPS (P11172)
Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRT) (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (ODC) (OMPD) (EC 4.1.1.23) (OMPdecase)]
Gene: UMPS
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18184586 |
| Identification Methods | x-ray crystallography, molecular sieving |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | OMPdecase~OMPdecase, OMPdecase~Pribosyltran, Pribosyltran~Pribosyltran |
| Common GO terms | GO:0004588 - orotate phosphoribosyltransferase activity GO:0004590 - orotidine-5'-phosphate decarboxylase activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 8 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
