HitPredict

Interactor 1: ODB2 (P11182)
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (BCKDH-E2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Gene: DBT

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 26643866, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 1215
+	Hs
		126282 ODPX_HUMAN (52-477): 3.12e-148: 434: 23.76		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		739334 ODO2_HUMAN (52-481): 3.5e-140: 412: 24.54		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		489836 ODP2_HUMAN (40-137): 9.92e-23: 103: 21.21		HDAC6_HUMAN (1-1215): 0: 1435: 100.00