Interactor 1: ITAM (P11215)
Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)
Gene: ITGAM

Interactor 2: SPI1 (P17947)
Transcription factor PU.1 (31 kDa-transforming protein)
Gene: SPI1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.706

The method score is based on:

Property Details
Experiments 8095266, 17203216, 19747912, 10411939, 21402070
Identification Methods electrophoretic mobility supershift assay, anti tag coimmunoprecipitation, electrophoretic mobility shift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:1904151 - positive regulation of microglial cell mediated cytotoxicity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1152
Hs

1 270
+ Hs
+ Hs

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Last updated: 15 Jul 2024