HitPredict

Interactor 1: PKHG3 (A1L390)
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene: PLEKHG3

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PH, PH~RhoGEF
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1219 Hs			1 1124
+	Hs
		1343778 PKHG1_HUMAN (45-981): 5.7e-143: 469: 33.61		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1273283 ARHG2_HUMAN (12-801): 7.51e-109: 367: 12.63		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1333747 ECT2_HUMAN (6-516): 7.33e-85: 298: 19.96		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Mm
		1207976 ARHGC_MOUSE (10-698): 3.62e-89: 319: 16.18		RTKN_MOUSE (721-1113): 1.3e-118: 379: 17.43