HitPredict

Interactor 1: RALA (P11233)
Ras-related protein Ral-A (EC 3.6.5.2)
Gene: RALA

Interactor 2: EXOC2 (Q96KP1)
Exocyst complex component 2 (Exocyst complex component Sec5)
Gene: EXOC2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	12839989, 12624092, 21241894, 17018283
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~TIG
Common GO terms	GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0090543 - Flemming body
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 924
+	Hs
		506472 RALB_HUMAN (1-206): 3.7e-91: 267: 81.64		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Hs
		914284 RB11A_HUMAN (4-204): 2.68e-77: 232: 28.04		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Dm
		819770 RALA_DROME (13-206): 1.89e-88: 260: 79.38		EXOC2_DROME (8-919): 0: 846: 32.80
+	Dm
		1280870 Q962I2_DROME (13-206): 5.73e-85: 251: 74.23		EXOC2_DROME (8-919): 0: 846: 32.80
+	Hs
		1070443 RAB35_HUMAN (8-204): 2.47e-85: 252: 31.53		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		914435 RB11A_HUMAN (4-204): 2.68e-77: 232: 28.04		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		348990 RASN_HUMAN (27-181): 1.39e-51: 166: 53.55		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		349712 RASH_HUMAN (27-180): 9.59e-52: 166: 53.90		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		350658 RASK_HUMAN (27-186): 2.13e-50: 163: 52.80		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16