HitPredict

Interactor 1: RALB (P11234)
Ras-related protein Ral-B (EC 3.6.5.2)
Gene: RALB

Interactor 2: EXOC2 (Q96KP1)
Exocyst complex component 2 (Exocyst complex component Sec5)
Gene: EXOC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	14525976, 24056301, 21241894, 27173435, 17018283
Identification Methods	two hybrid, affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Ras~TIG
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 206 Hs			1 924
+	Hs
		506414 RALA_HUMAN (1-206): 1.04e-86: 256: 81.64		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Hs
		914284 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		EXOC2_HUMAN (1-924): 0: 1074: 100.00
+	Dm
		819770 RALA_DROME (13-206): 2.78e-92: 270: 75.26		EXOC2_DROME (8-919): 0: 846: 32.80
+	Dm
		1280870 Q962I2_DROME (13-186): 1.08e-89: 263: 78.16		EXOC2_DROME (8-919): 0: 846: 32.80
+	Hs
		914435 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		349712 RASH_HUMAN (27-181): 3.76e-49: 160: 52.90		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		348990 RASN_HUMAN (27-191): 8.77e-49: 159: 50.00		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16
+	Hs
		350658 RASK_HUMAN (27-198): 2.81e-47: 155: 50.00		VPS51_HUMAN (150-899): 1.2e-173: 525: 14.16