HitPredict

Interactor 1: RALB (P11234)
Ras-related protein Ral-B (EC 3.6.5.2)
Gene: RALB

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37506885
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 206 Hs			1 729
+	Mm
		895598 RAB8B_MOUSE (7-206): 1.54e-75: 227: 30.62		TBK1_MOUSE (1-729): 0: 558: 94.10
+	Hs
		896616 RAB14_HUMAN (1-199): 1.59e-75: 228: 30.00		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		914067 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		254466 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		ROCK2_HUMAN (7-724): 1.1e-114: 378: 16.52
+	Hs
		914124 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	At
		221736 RAA1E_ARATH (2-204): 7.14e-76: 228: 29.03		KIN10_ARATH (8-395): 3.62e-117: 363: 20.05
+	Hs
		625461 RB11B_HUMAN (5-204): 1.29e-75: 228: 29.17		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		254429 RASH_HUMAN (27-181): 3.76e-49: 160: 52.90		ROCK2_HUMAN (7-724): 1.1e-114: 378: 16.52
+	Hs
		254428 RASN_HUMAN (27-191): 8.77e-49: 159: 50.00		ROCK2_HUMAN (7-724): 1.1e-114: 378: 16.52
+	Hs
		254430 RASK_HUMAN (27-198): 2.81e-47: 155: 50.00		ROCK2_HUMAN (7-724): 1.1e-114: 378: 16.52
+	Hs
		349389 RASH_HUMAN (27-181): 3.76e-49: 160: 52.90		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Hs
		348715 RASN_HUMAN (27-191): 8.77e-49: 159: 50.00		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Hs
		349030 RASN_HUMAN (27-191): 8.77e-49: 159: 50.00		MRCKB_HUMAN (6-700): 1.77e-108: 364: 16.10
+	Hs
		349133 RASH_HUMAN (27-181): 3.76e-49: 160: 52.90		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		647864 RB11A_HUMAN (5-204): 1.06e-75: 228: 29.44		MARK3_HUMAN (9-267): 1.86e-85: 287: 28.08
+	Hs
		349139 RASH_HUMAN (27-181): 3.76e-49: 160: 52.90		MARK3_HUMAN (9-267): 1.86e-85: 287: 28.08
+	Hs
		348523 RASN_HUMAN (27-191): 8.77e-49: 159: 50.00		MARK3_HUMAN (9-267): 1.86e-85: 287: 28.08
+	Hs
		262253 RAB1A_HUMAN (5-204): 2.25e-81: 242: 31.07		ULK1_HUMAN (13-222): 2.86e-26: 117: 34.10
+	Hs
		262229 RALB_HUMAN (1-206): 1.73e-80: 240: 100.00		ULK1_HUMAN (13-222): 2.86e-26: 117: 34.10
+	At
		1107296 RAA1B_ARATH (2-204): 1.41e-80: 240: 28.70		M3KE1_ARATH (4-221): 2.37e-21: 102: 32.13