HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1271 Hs			1 937
+	Hs
		321473 BCR_HUMAN (1-1271): 0: 1005: 100.00		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		925876 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Rn
		923861 ITSN1_RAT (74-927): 1.69e-77: 284: 13.61		AP2B1_RAT (1-937): 0: 926: 100.00
+	Hs
		925944 RHG18_HUMAN (919-1256): 1.73e-73: 260: 20.17		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		926012 ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		1014017 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		1014048 RHG18_HUMAN (919-1256): 1.73e-73: 260: 20.17		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		69207 A9UF07_HUMAN (690-1072): 3.04e-27: 122: 60.83		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		925874 RBP1_HUMAN (1051-1211): 4.99e-20: 98.2: 34.55		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		1014016 RBP1_HUMAN (1051-1211): 4.99e-20: 98.2: 34.55		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		321552 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Rn
		88768 ITSN1_RAT (74-927): 1.69e-77: 284: 13.61		D3ZUY8_RAT (11-932): 0: 625: 17.14
+	Hs
		302157 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		AP2A2_HUMAN (11-933): 0: 600: 16.99
+	Hs
		302183 RHG18_HUMAN (919-1256): 1.73e-73: 260: 20.17		AP2A2_HUMAN (11-933): 0: 600: 16.99
+	Hs
		1032729 PREX1_HUMAN (447-1058): 2.05e-83: 302: 15.70		AP3B2_HUMAN (16-594): 2.55e-174: 537: 28.71
+	Hs
		863337 ARGAL_HUMAN (467-779): 1.34e-71: 264: 26.16		COPB_HUMAN (8-927): 0: 561: 12.47
+	Hs
		212646 RHG18_HUMAN (919-1256): 1.73e-73: 260: 20.17		AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57
+	Hs
		69200 A9UF07_HUMAN (690-1072): 3.04e-27: 122: 60.83		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		321551 RBP1_HUMAN (1051-1211): 4.99e-20: 98.2: 34.55		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		302153 RBP1_HUMAN (1051-1211): 4.99e-20: 98.2: 34.55		AP2A2_HUMAN (11-933): 0: 600: 16.99