HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: NHRF3 (Q5T2W1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3) (CFTR-associated protein of 70 kDa) (Na(+)/H(+) exchanger regulatory factor 3) (Na/Pi cotransporter C-terminal-associated protein 1) (NaPi-Cap1) (PDZ domain-containing protein 1) (Sodium-hydrogen exchanger regulatory factor 3)
Gene: PDZK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, 15494376
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1271 Hs			1 519
+	Hs
		506645 BCR_HUMAN (1-1271): 0: 1005: 100.00		MAGI1_HUMAN (183-460): 1.21e-20: 98.3: 19.89
+	Hs
		506626 BCR_HUMAN (1-1271): 0: 1005: 100.00		LNX1_HUMAN (4-213): 1.57e-20: 97.1: 16.74
+	Hs
		67905 BCR_HUMAN (1-1271): 0: 1005: 100.00		PDZ1P_HUMAN (6-134): 6.25e-18: 87.9: 28.68
+	Mm
		250626 BCR_MOUSE (1-1271): 0: 941: 93.79		LNX1_MOUSE (2-213): 1.09e-19: 94.8: 15.70
+	Mm
		1131438 ABR_MOUSE (419-1271): 0: 563: 66.00		DLG4_MOUSE (3-344): 3.77e-36: 144: 16.96
+	Hs
		1021847 ABR_HUMAN (419-1271): 0: 567: 66.47		LNX1_HUMAN (4-213): 1.57e-20: 97.1: 16.74
+	Hs
		299264 FARP2_HUMAN (356-812): 1.08e-68: 253: 18.26		NHRF3_HUMAN (1-519): 1.87e-114: 350: 100.00
+	Hs
		1271019 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		DLG3_HUMAN (3-359): 3.36e-32: 133: 17.27
+	Mm
		88351 D3YYY8_MOUSE (77-802): 1e-76: 274: 14.60		DLG4_MOUSE (3-344): 3.77e-36: 144: 16.96
+	Hs
		1050027 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		1021546 ARHGQ_HUMAN (79-816): 3.76e-86: 302: 16.02		DLG1_HUMAN (289-461): 1.6e-16: 85.1: 18.52
+	Hs
		1075407 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17
+	Mm
		250653 SRGP1_MOUSE (596-1261): 7.92e-76: 275: 14.35		LNX1_MOUSE (2-213): 1.09e-19: 94.8: 15.70
+	Hs
		1173142 SYDE1_HUMAN (909-1264): 2.03e-75: 268: 29.35		MAGI1_HUMAN (183-460): 1.21e-20: 98.3: 19.89
+	Mm
		57852 KALRN_MOUSE (457-1087): 8.9e-58: 222: 14.39		DLG4_MOUSE (3-344): 3.77e-36: 144: 16.96
+	Hs
		1049703 ARHG7_HUMAN (369-1044): 2.29e-75: 269: 13.98		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		856141 CHIO_HUMAN (782-1248): 4.7e-79: 270: 18.32		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17
+	Hs
		1049707 ARHG7_HUMAN (369-1044): 2.29e-75: 269: 13.98		NHRF2_HUMAN (5-146): 7.72e-20: 92.8: 28.17
+	Hs
		1050065 ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07		SCRIB_HUMAN (125-505): 6.83e-20: 96: 10.97
+	Hs
		224721 KALRN_HUMAN (457-1087): 1.21e-57: 222: 14.20		LNX1_HUMAN (4-213): 1.57e-20: 97.1: 16.74