HitPredict

Interactor 1: SPTB1 (P11277)
Spectrin beta chain, erythrocytic (Beta-I spectrin)
Gene: SPTB

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2137 Hs			1 245
+	Mm
		434798 SPTA1_MOUSE (305-2085): 0: 622: 19.47		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		360618 SPTA1_HUMAN (309-1848): 2.06e-131: 463: 18.73		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		211554 ACTN4_HUMAN (53-728): 4.25e-119: 403: 37.29		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		211558 ACTN4_HUMAN (53-728): 4.25e-119: 403: 37.29		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		211551 ACTN4_HUMAN (53-728): 4.25e-119: 403: 37.29		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Mm
		82753 B9EKJ1_MOUSE (187-1410): 4.01e-42: 173: 17.49		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		297821 K0754_HUMAN (245-1861): 4.48e-36: 153: 12.53		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Mm
		926889 PLEC_MOUSE (257-1706): 3.86e-38: 160: 9.99		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		297824 K0754_HUMAN (245-1861): 4.48e-36: 153: 12.53		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Mm
		926814 Q68FG2_MOUSE (826-2117): 1.47e-35: 151: 17.23		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		910159 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		297815 K0754_HUMAN (245-1861): 4.48e-36: 153: 12.53		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		647380 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927659 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683813 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		82777 B9EKJ1_MOUSE (187-1410): 4.01e-42: 173: 17.49		1433B_MOUSE (1-242): 2.84e-124: 354: 80.99
+	Hs
		683333 SPTN1_HUMAN (274-1229): 4.85e-22: 107: 17.36		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		684396 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982620 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		905261 MACF1_HUMAN (287-1191): 6e-32: 140: 16.18		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33