HitPredict

Interactor 1: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Interactor 2: ETS2 (P15036)
Protein C-ets-2
Gene: ETS2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 9334186, 9681824
Identification Methods two hybrid, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ets~Ets, Ets~Ets1_N_flank, SAM_PNT~SAM_PNT
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
and 5 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 479
Hs

1 469
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024