Interactor 1: RAF1 (P11345)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RASH (P20171)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: Hras

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 9679960
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Ras, Pkinase~Ras, RBD~Ras
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
GO:0008285 - negative regulation of cell population proliferation
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024