Interactor 1: RAF1 (P11345)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1
Interactor 2: PAK1 (P35465)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (Protein kinase MUK2) (p21-activated kinase 1) (PAK-1) (p68-PAK)
Gene: PAK1
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.47 | 1.00 | 0.692 |
The method score is based on:
Property | Details |
---|---|
Experiments | 20637424 |
Identification Methods | protein kinase assay |
Interaction Type | direct interaction, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | C1_1~Pkinase, PBD~Pkinase, Pkinase~Pkinase |
Common GO terms | GO:0001666 - response to hypoxia GO:0001934 - positive regulation of protein phosphorylation GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0004709 - MAP kinase kinase kinase activity and 8 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024