HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: FGF3 (P11487)
Fibroblast growth factor 3 (FGF-3) (Heparin-binding growth factor 3) (HBGF-3) (Proto-oncogene Int-2)
Gene: FGF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	18199118
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FGF~I-set
Common GO terms	GO:0005576 - extracellular region GO:0008284 - positive regulation of cell population proliferation GO:0008543 - fibroblast growth factor receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 239
+	Hs
		507874 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF9_HUMAN (14-198): 4.02e-67: 207: 36.41
+	Mm
		555263 FGFR1_MOUSE (1-822): 0: 860: 98.42		FGF9_MOUSE (14-198): 5.63e-67: 207: 36.41
+	Hs
		181657 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF10_HUMAN (29-183): 6.03e-63: 197: 47.44
+	Hs
		441802 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF4_HUMAN (17-182): 7.74e-57: 181: 30.95
+	Hs
		499375 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF6_HUMAN (16-182): 2.49e-54: 175: 33.14
+	Hs
		507815 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF5_HUMAN (44-200): 7.48e-52: 170: 39.75
+	Mm
		549545 FGFR1_MOUSE (1-822): 0: 860: 98.42		FGF2_MOUSE (17-181): 2.88e-53: 170: 35.50
+	Mm
		555272 FGFR1_MOUSE (1-822): 0: 860: 98.42		FGF23_MOUSE (18-201): 1.58e-51: 169: 25.77
+	Hs
		447013 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF2_HUMAN (24-181): 9.38e-50: 166: 36.88
+	Hs
		508186 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF23_HUMAN (16-217): 1.16e-48: 162: 28.78
+	Hs
		507927 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF8_HUMAN (43-217): 1.18e-48: 161: 26.67
+	Hs
		399128 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF1_HUMAN (40-186): 3.69e-49: 160: 34.90
+	Mm
		555273 FGFR1_MOUSE (1-822): 0: 860: 98.42		FGF21_MOUSE (32-205): 3.7e-46: 154: 27.37
+	Hs
		320638 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF19_HUMAN (24-192): 2.18e-45: 152: 28.65
+	Hs
		181659 FGFR2_HUMAN (1-821): 0: 803: 71.21		FGF10_HUMAN (29-183): 6.03e-63: 197: 47.44
+	Hs
		225915 FGFR1_HUMAN (1-822): 0: 861: 100.00		FGF17_HUMAN (42-201): 2.04e-35: 126: 23.08
+	Hs
		441808 FGFR2_HUMAN (1-821): 0: 803: 71.21		FGF4_HUMAN (17-182): 7.74e-57: 181: 30.95
+	Hs
		447019 FGFR2_HUMAN (1-821): 0: 803: 71.21		FGF2_HUMAN (24-181): 9.38e-50: 166: 36.88
+	Hs
		399132 FGFR2_HUMAN (1-821): 0: 803: 71.21		FGF1_HUMAN (40-186): 3.69e-49: 160: 34.90
+	Hs
		225918 FGFR2_HUMAN (1-821): 0: 803: 71.21		FGF17_HUMAN (42-201): 2.04e-35: 126: 23.08