HitPredict

Interactor 1: ELOV7 (A1L3X0)
Very long chain fatty acid elongase 7 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Elongation of very long chain fatty acids protein 7) (Very long chain 3-ketoacyl-CoA synthase 7) (Very long chain 3-oxoacyl-CoA synthase 7)
Gene: ELOVL7

Interactor 2: CERS2 (Q96G23)
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297)
Gene: CERS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20937905
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0030148 - sphingolipid biosynthetic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 380
+	Hs
		1291795 ELOV1_HUMAN (11-272): 7.1e-102: 300: 59.16		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Hs
		1291800 ELOV4_HUMAN (10-278): 9.37e-97: 288: 45.02		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Hs
		1291817 ELOV2_HUMAN (13-277): 7.44e-84: 255: 40.66		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Hs
		1291819 ELOV5_HUMAN (13-264): 1.56e-82: 251: 37.70		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Hs
		1291811 ELOV3_HUMAN (16-270): 1.58e-50: 169: 26.72		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Hs
		1291806 ELOV6_HUMAN (29-272): 3.42e-44: 152: 26.67		CERS2_HUMAN (1-380): 6.94e-161: 457: 100.00
+	Sc
		752766 ELO3_YEAST (58-261): 2.69e-34: 128: 26.24		LAG1_YEAST (116-356): 1.97e-68: 222: 24.31
+	Sc
		659164 ELO3_YEAST (58-261): 2.69e-34: 128: 26.24		LAC1_YEAST (116-337): 1.78e-60: 202: 20.76