Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: FGF9 (P31371)
Fibroblast growth factor 9 (FGF-9) (Glia-activating factor) (GAF) (Heparin-binding growth factor 9) (HBGF-9)
Gene: FGF9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.738

The method score is based on:

Property Details
Experiments 18199118, 14613973
Identification Methods unspecified method, surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0002062 - chondrocyte differentiation
GO:0005576 - extracellular region
and 11 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024