HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.975

Property	Details
Experiments	18497817, 25702870, 27396824, 30664872, 32857986, 18497827, 24361330, 28190767, 31699778, 23153250, 20059542
Identification Methods	two hybrid, pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Rpn13_ADRM1_Pru~ubiquitin, RPN13_C~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 407
+	Rn
		1224541 UBC_RAT (1-637): 0: 779: 98.90		ADRM1_RAT (1-407): 5.93e-166: 473: 96.56
+	Hs
		987046 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		ADRM1_HUMAN (1-407): 8.81e-165: 470: 100.00
+	Mm
		509300 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		ADRM1_MOUSE (1-407): 8.67e-161: 459: 96.56
+	Hs
		507205 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		ADRM1_HUMAN (1-407): 8.81e-165: 470: 100.00