HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: NOSTN (Q8IVI9)
Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)
Gene: NOSTRIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.740

Property	Details
Experiments	22751148
Identification Methods	pull down, two hybrid, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 506
+	Mm
		555266 FGFR1_MOUSE (1-822): 0: 860: 98.42		NOSTN_MOUSE (1-506): 4.69e-76: 249: 82.61
+	Hs
		508265 FGFR1_HUMAN (1-822): 0: 861: 100.00		PACN2_HUMAN (6-496): 8.61e-55: 193: 15.22
+	Hs
		507966 FGFR1_HUMAN (1-822): 0: 861: 100.00		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		508201 FGFR1_HUMAN (1-822): 0: 861: 100.00		PPIP2_HUMAN (6-305): 1.11e-40: 151: 19.00
+	Hs
		508156 FGFR1_HUMAN (1-822): 0: 861: 100.00		FNBP1_HUMAN (12-384): 4.2e-38: 149: 16.05
+	Hs
		508169 FGFR1_HUMAN (1-822): 0: 861: 100.00		SH3G1_HUMAN (132-500): 7.33e-38: 144: 19.20
+	Hs
		508140 FGFR1_HUMAN (1-822): 0: 861: 100.00		SH3K1_HUMAN (445-506): 1.13e-14: 78.8: 35.94
+	Hs
		508051 FGFR1_HUMAN (1-822): 0: 861: 100.00		FBP1L_HUMAN (291-492): 3.29e-11: 67.6: 15.69
+	Hs
		508233 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN2_HUMAN (429-499): 1.1e-10: 66.5: 29.58
+	Hs
		508022 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN1_HUMAN (424-504): 3.46e-09: 61.8: 25.58
+	Hs
		601605 FGFR2_HUMAN (1-821): 0: 803: 71.21		ITSN2_HUMAN (429-499): 1.1e-10: 66.5: 29.58
+	Hs
		608196 FGFR4_HUMAN (29-808): 0: 664: 55.60		PACN2_HUMAN (6-496): 8.61e-55: 193: 15.22
+	Hs
		607952 FGFR4_HUMAN (29-808): 0: 664: 55.60		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		608135 FGFR4_HUMAN (29-808): 0: 664: 55.60		PPIP2_HUMAN (6-305): 1.11e-40: 151: 19.00
+	Hs
		665588 EPHB2_HUMAN (4-819): 0: 640: 18.07		FCHO2_HUMAN (11-436): 3.58e-44: 168: 14.45
+	Hs
		297957 FGFR3_HUMAN (6-821): 0: 730: 61.22		FCSD2_HUMAN (28-504): 1.51e-12: 72.2: 11.45
+	Hs
		608003 FGFR4_HUMAN (29-808): 0: 664: 55.60		FBP1L_HUMAN (291-492): 3.29e-11: 67.6: 15.69
+	Hs
		608159 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN2_HUMAN (429-499): 1.1e-10: 66.5: 29.58
+	Hs
		607984 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN1_HUMAN (424-504): 3.46e-09: 61.8: 25.58
+	Hs
		665608 EPHB2_HUMAN (4-819): 0: 640: 18.07		ITSN1_HUMAN (424-504): 3.46e-09: 61.8: 25.58