HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 822 Hs			1 435
+	Hs
		508180 FGFR1_HUMAN (1-822): 0: 861: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		665310 EPHA2_HUMAN (3-819): 0: 583: 18.68		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		609222 FGFR3_HUMAN (6-821): 0: 730: 61.22		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	Mm
		546292 NTRK2_MOUSE (111-762): 1.43e-163: 497: 23.74		AP2M1_MOUSE (1-435): 1.03e-178: 507: 100.00
+	Hs
		385470 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		608213 FGFR4_HUMAN (29-808): 0: 664: 55.60		STON1_HUMAN (149-408): 2.5e-58: 205: 21.75
+	Hs
		385759 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66