HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: E41LA (Q9HCS5)
Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4)
Gene: EPB41L4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 686
+	Hs
		508287 FGFR1_HUMAN (1-822): 0: 861: 100.00		FARP1_HUMAN (9-429): 1.98e-119: 383: 26.48
+	Hs
		507828 FGFR1_HUMAN (1-822): 0: 861: 100.00		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		507865 FGFR1_HUMAN (1-822): 0: 861: 100.00		MOES_HUMAN (7-555): 4.9e-113: 353: 18.00
+	Hs
		507884 FGFR1_HUMAN (1-822): 0: 861: 100.00		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		665337 EPHA2_HUMAN (3-819): 0: 583: 18.68		E41LA_HUMAN (1-686): 0: 575: 100.00
+	Hs
		505551 FGFR3_HUMAN (6-821): 0: 730: 61.22		EPB41_HUMAN (9-675): 1.72e-126: 397: 24.78
+	Hs
		299238 FGFR3_HUMAN (6-821): 0: 730: 61.22		FARP2_HUMAN (8-560): 2.16e-123: 394: 24.96
+	Hs
		546928 FGFR4_HUMAN (29-808): 0: 664: 55.60		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		607883 FGFR4_HUMAN (29-808): 0: 664: 55.60		MOES_HUMAN (7-555): 4.9e-113: 353: 18.00
+	Hs
		607900 FGFR4_HUMAN (29-808): 0: 664: 55.60		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		640048 EPHB2_HUMAN (4-819): 0: 640: 18.07		MOES_HUMAN (7-555): 4.9e-113: 353: 18.00
+	Hs
		665554 EPHB2_HUMAN (4-819): 0: 640: 18.07		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Mm
		546328 NTRK2_MOUSE (111-762): 1.43e-163: 497: 23.74		E41L3_MOUSE (4-684): 2.39e-157: 479: 27.02
+	Hs
		546943 EPHA2_HUMAN (3-819): 0: 583: 18.68		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		665158 EPHA2_HUMAN (3-819): 0: 583: 18.68		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10
+	Hs
		674528 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		E41L1_HUMAN (9-665): 9.7e-142: 437: 25.48
+	Hs
		1083898 NTRK2_HUMAN (102-762): 5.62e-163: 495: 22.70		E41L5_HUMAN (8-414): 2.29e-126: 393: 37.23
+	Hs
		505564 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		EPB41_HUMAN (9-675): 1.72e-126: 397: 24.78
+	Hs
		204618 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		E41L2_HUMAN (8-635): 1.98e-121: 387: 23.56
+	Hs
		719502 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		MERL_HUMAN (6-570): 1.28e-111: 350: 20.10