HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005829 - cytosol GO:0016477 - cell migration GO:0018108 - peptidyl-tyrosine phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 513
+	Hs
		508097 FGFR1_HUMAN (1-822): 0: 861: 100.00		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		508262 FGFR1_HUMAN (1-822): 0: 861: 100.00		ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66
+	Hs
		203204 FGFR1_HUMAN (1-822): 0: 861: 100.00		SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92
+	Hs
		507829 FGFR1_HUMAN (1-822): 0: 861: 100.00		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Hs
		608156 FGFR4_HUMAN (29-808): 0: 664: 55.60		ABI2_HUMAN (1-513): 1.82e-91: 290: 100.00
+	Hs
		507939 FGFR1_HUMAN (1-822): 0: 861: 100.00		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		665629 EPHB2_HUMAN (4-819): 0: 640: 18.07		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		508233 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN2_HUMAN (289-512): 5.53e-14: 77.2: 15.63
+	Hs
		508022 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN1_HUMAN (380-510): 4.82e-12: 71: 15.22
+	Hs
		601492 FGFR2_HUMAN (1-821): 0: 803: 71.21		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		601605 FGFR2_HUMAN (1-821): 0: 803: 71.21		ITSN2_HUMAN (289-512): 5.53e-14: 77.2: 15.63
+	Hs
		608185 FGFR4_HUMAN (29-808): 0: 664: 55.60		ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66
+	Hs
		609244 FGFR3_HUMAN (6-821): 0: 730: 61.22		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		607935 FGFR4_HUMAN (29-808): 0: 664: 55.60		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		608159 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN2_HUMAN (289-512): 5.53e-14: 77.2: 15.63
+	Hs
		607984 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN1_HUMAN (380-510): 4.82e-12: 71: 15.22
+	Hs
		665389 EPHA3_HUMAN (3-775): 0: 643: 19.03		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		665574 EPHB2_HUMAN (4-819): 0: 640: 18.07		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Mm
		872621 EPHB2_MOUSE (4-819): 0: 640: 17.95		GRB2_MOUSE (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		665608 EPHB2_HUMAN (4-819): 0: 640: 18.07		ITSN1_HUMAN (380-510): 4.82e-12: 71: 15.22