Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 37827155
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003697 - single-stranded DNA binding
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 765
Hs

1 121
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024