Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1
Interactor 2: TOP1M (Q969P6)
DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.6.2.1)
Gene: TOP1MT
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Topo_C_assoc~Topoisom_I, Topoisom_I~Topoisom_I_N |
| Common GO terms | GO:0003677 - DNA binding GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity GO:0005654 - nucleoplasm GO:0005694 - chromosome GO:0005730 - nucleolus and 3 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
