Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.55 0.628

The method score is based on:

Property Details
Experiments 27684187, 16230076, 17983804
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, fluorescence microscopy, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0032991 - protein-containing complex
and 2 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024