HitPredict

Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: CTCF (P49711)
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)
Gene: CTCF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 34591612, 14759373
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000793 - condensed chromosome
GO:0001673 - male germ cell nucleus
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 727
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024