Interactor 1: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 28977666
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 2000
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Dm

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Last updated: 15 Jul 2024