HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: ATO (P48987)
Protein atonal
Gene: ATO

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.829

Property	Details
Experiments	26824657, 15748845, 15084454
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0007423 - sensory organ development GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity and 1 others more... GO:0048663 - neuron fate commitment
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 312
+	Dm
		509356 DA_DROME (1-710): 0: 908: 100.00		MYOD_DROME (146-312): 1.22e-26: 108: 25.41
+	Dm
		496114 DA_DROME (1-710): 0: 908: 100.00		TWIST_DROME (175-311): 5.93e-25: 106: 29.79
+	Dm
		509388 DA_DROME (1-710): 0: 908: 100.00		Q9W4X2_DROME (145-312): 1.22e-25: 106: 21.08
+	Dm
		509377 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (210-311): 4.23e-25: 101: 32.35
+	Dm
		509380 DA_DROME (1-710): 0: 908: 100.00		Q9VL05_DROME (220-311): 6.31e-25: 100: 32.61
+	Dm
		509390 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (252-311): 4.91e-24: 98.7: 70.00
+	Dm
		80865 DA_DROME (1-710): 0: 908: 100.00		DIMM_DROME (242-311): 3.73e-20: 91.7: 41.43
+	Mm
		550212 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TFE2_MOUSE (134-312): 2.11e-25: 108: 22.22
+	Mm
		603985 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (210-311): 5.24e-26: 106: 35.29
+	Mm
		1142072 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (202-311): 4.24e-25: 101: 29.09
+	Mm
		644476 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (147-312): 9.16e-25: 100: 23.49
+	Hs
		1039378 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		NDF1_HUMAN (164-312): 2.76e-28: 113: 26.75
+	Hs
		551571 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TFE2_HUMAN (125-312): 7.29e-26: 109: 20.64
+	Hs
		568226 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL1_HUMAN (210-311): 6.7e-26: 106: 35.29
+	Hs
		210863 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF21_HUMAN (193-311): 1.91e-26: 104: 28.89
+	Hs
		1018388 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF15_HUMAN (195-311): 6.44e-26: 103: 35.04
+	Hs
		899129 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND2_HUMAN (202-311): 4.24e-25: 101: 29.09
+	Hs
		971805 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN1_HUMAN (186-311): 8.63e-26: 101: 23.02
+	Hs
		1083176 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL2_HUMAN (254-311): 9.26e-26: 100: 44.83
+	Hs
		971838 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN2_HUMAN (197-311): 5.49e-25: 99.2: 29.23