HitPredict

Interactor 1: DA (P11420)
Protein daughterless
Gene: DA

Interactor 2: Q9VL05 (Q9VL05)
FI14601p (Hand)
Gene: Hand

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	23747982
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 710 Dm			1 174
+	Dm
		1197459 Q86PA6_DROME (1-697): 0: 912: 96.84		Q86PA6_DROME (18-174): 4.77e-28: 111: 21.43
+	Dm
		509351 DA_DROME (1-710): 0: 908: 100.00		DA_DROME (18-174): 7.77e-28: 110: 21.43
+	Dm
		509377 DA_DROME (1-710): 0: 908: 100.00		FER3_DROME (19-174): 5.72e-29: 107: 22.44
+	Dm
		509364 DA_DROME (1-710): 0: 908: 100.00		ATO_DROME (1-115): 8.38e-25: 99.2: 28.45
+	Dm
		509356 DA_DROME (1-710): 0: 908: 100.00		MYOD_DROME (6-143): 4.19e-23: 95.3: 18.06
+	Dm
		496114 DA_DROME (1-710): 0: 908: 100.00		TWIST_DROME (51-118): 4.62e-22: 93.7: 45.59
+	Dm
		509390 DA_DROME (1-710): 0: 908: 100.00		AMOS_DROME (53-118): 4.14e-23: 92.5: 42.42
+	Dm
		185785 DA_DROME (1-710): 0: 908: 100.00		O18374_DROME (49-116): 1.12e-20: 87.1: 39.71
+	Dm
		509369 DA_DROME (1-710): 0: 908: 100.00		Q0IGU7_DROME (49-116): 1.15e-20: 87.1: 39.71
+	Mm
		1142072 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND2_MOUSE (11-169): 2.6e-27: 103: 45.12
+	Mm
		603985 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TAL1_MOUSE (53-130): 9.89e-26: 102: 42.31
+	Mm
		644476 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		TWST1_MOUSE (50-123): 1.6e-26: 101: 52.00
+	Mm
		1142446 HTF4_MOUSE (219-662): 1.64e-142: 435: 35.32		HAND1_MOUSE (37-169): 5.58e-25: 97.6: 45.07
+	Hs
		899129 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND2_HUMAN (11-169): 2.6e-27: 103: 45.12
+	Hs
		568226 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TAL1_HUMAN (53-130): 4.41e-25: 100: 42.31
+	Hs
		971805 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN1_HUMAN (58-115): 6.46e-27: 100: 50.00
+	Hs
		238594 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		MUSC_HUMAN (57-122): 1.25e-24: 96.7: 45.46
+	Hs
		971838 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HEN2_HUMAN (62-115): 1.76e-25: 96.7: 50.00
+	Hs
		330430 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		HAND1_HUMAN (40-169): 3.1e-24: 95.7: 45.65
+	Hs
		210863 HTF4_HUMAN (219-662): 5.86e-134: 412: 35.33		TCF21_HUMAN (13-126): 4.36e-24: 94.5: 31.58