HitPredict

Interactor 1: CDK1 (P11440)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNB1 (P24860)
G2/mitotic-specific cyclin-B1
Gene: CCNB1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 19553603, 12121977, 10559244, 9247342, 22649246, 17283331, 23108051
Identification Methods enzymatic study, pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005759 - mitochondrial matrix
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0010629 - negative regulation of gene expression
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Mm

1 430
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024