Interactor 1: CDK1 (P11440)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CDN1A (P39689)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein) (p21)
Gene: Cdkn1a

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 14749395
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007095 - mitotic G2 DNA damage checkpoint signaling
GO:0010629 - negative regulation of gene expression
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Mm

1 159
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Xl
+ Xl
+ Hs
+ Hs
+ Mm
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024