HitPredict

Interactor 1: CDK1 (P11440)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNA2 (P51943)
Cyclin-A2 (Cyclin-A)
Gene: CCNA2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 8226784, 19592082
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Mm

1 422
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Mm
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+ Mm
+ Hs
+ At
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+ Gg
+ Xl
+ At
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+ At
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024