HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 525
+	Hs
		475345 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KS6B1_HUMAN (8-525): 0: 573: 100.00
+	Hs
		681773 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		509505 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		KPCA_HUMAN (4-419): 2.83e-142: 426: 35.55
+	Hs
		923962 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		KPCE_HUMAN (13-420): 6.39e-143: 430: 33.89
+	Hs
		474936 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT2_HUMAN (3-416): 5.02e-151: 442: 38.66
+	Hs
		474935 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		475390 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Rn
		934619 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KPCB_RAT (35-422): 4.52e-146: 436: 36.92
+	Hs
		408534 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92
+	Hs
		681774 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		AKT1_HUMAN (34-418): 1.81e-150: 440: 39.90
+	Hs
		408535 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92
+	Hs
		408593 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		KPCB_HUMAN (35-422): 2.03e-146: 437: 36.92
+	Hs
		475314 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCA_HUMAN (4-419): 2.83e-142: 426: 35.55
+	Hs
		116959 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		SGK1_HUMAN (79-417): 5.26e-101: 312: 46.44