HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: CDK18 (Q07002)
Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)
Gene: CDK18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	26496610, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 474
+	Hs
		625332 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		475633 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		CDK17_HUMAN (6-474): 1.13e-147: 433: 62.26
+	Dm
		114962 Q8IGR0_DROME (1-123): 4.88e-39: 131: 28.46		M9PE01_DROME (4-462): 1.16e-133: 398: 43.09
+	At
		1091646 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		MPK4_ARATH (110-466): 7.26e-137: 400: 29.04
+	Hs
		414696 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		CDK1_HUMAN (141-430): 6.84e-137: 397: 51.54
+	At
		621654 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		CDKA1_ARATH (141-429): 2.4e-136: 396: 52.40
+	At
		1091645 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		MPK3_ARATH (130-462): 3.92e-134: 393: 30.79
+	Hs
		841149 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		CDK7_HUMAN (138-470): 1.68e-134: 393: 35.59
+	Rn
		974743 UBC_RAT (1-102): 9.46e-29: 112: 31.13		CDK5_RAT (141-431): 1.82e-132: 386: 54.95
+	Sc
		339331 RS31_YEAST (1-122): 3.56e-31: 111: 29.51		CDK1_YEAST (139-427): 1.47e-128: 376: 50.00
+	Sc
		477595 RL40A_YEAST (1-72): 1.75e-29: 106: 41.67		PHO85_YEAST (143-427): 1.26e-129: 379: 52.54