HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031647 - regulation of protein stability
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Hs			1 399
+	Mm
		57049 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		DDI2_MOUSE (1-399): 5.29e-160: 457: 95.99
+	Rn
		48892 UBC_RAT (1-102): 9.46e-29: 112: 31.13		DDI1_RAT (1-398): 6.1e-151: 434: 71.12
+	Dm
		547961 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		Q9VXF9_DROME (5-395): 2.61e-124: 368: 46.38
+	Hs
		509747 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		924216 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		924208 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Dm
		547958 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Rn
		1144285 UBC_RAT (1-102): 9.46e-29: 112: 31.13		UBQL1_RAT (5-241): 8.63e-50: 178: 15.20
+	Rn
		88976 UBC_RAT (1-102): 9.46e-29: 112: 31.13		D4AA63_RAT (5-241): 5.88e-44: 163: 15.27
+	Hs
		803643 UBL4B_HUMAN (1-146): 2.55e-47: 153: 44.52		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Dm
		547946 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88
+	Hs
		509538 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		100136 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		F6VEM6_HUMAN (4-167): 4.14e-29: 115: 15.61
+	Hs
		872136 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Rn
		1144200 UBC_RAT (1-102): 9.46e-29: 112: 31.13		BAG6_RAT (4-180): 1.87e-27: 116: 14.21
+	Rn
		1140100 UBC_RAT (1-102): 9.46e-29: 112: 31.13		Q5XFX7_RAT (3-198): 4.5e-28: 114: 14.50
+	Hs
		509615 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Hs
		923944 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Bt
		924446 RS27A_BOVIN (1-123): 2.9e-40: 134: 28.46		RS27A_BOVIN (10-77): 3.2e-14: 71.7: 22.06
+	Rn
		924232 UBC_RAT (1-102): 9.46e-29: 112: 31.13		RS27A_RAT (10-77): 3.2e-14: 71.7: 22.06