HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: ULK4 (Q96C45)
Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)
Gene: ULK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 1275
+	Dm
		90528 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		E1JGN0_DROME (3-702): 3.33e-154: 495: 15.80
+	Hs
		681773 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		AKT1_HUMAN (1-349): 3.89e-122: 389: 21.33
+	At
		1091641 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		KIN10_ARATH (3-421): 5.91e-128: 405: 20.55
+	At
		955189 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		KIN11_ARATH (3-365): 1.02e-124: 397: 22.34
+	Hs
		474936 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT2_HUMAN (1-352): 2.93e-123: 392: 21.21
+	Hs
		474935 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT1_HUMAN (1-349): 3.89e-122: 389: 21.33
+	Hs
		475390 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		AKT1_HUMAN (1-349): 3.89e-122: 389: 21.33
+	Hs
		681774 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		AKT1_HUMAN (1-349): 3.89e-122: 389: 21.33
+	At
		98421 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		RUK_ARATH (1-738): 1.6e-95: 337: 20.54
+	Hs
		330966 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		PAK4_HUMAN (1-283): 4.97e-25: 113: 29.37
+	Hs
		475928 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		ULK3_HUMAN (1-279): 2.62e-32: 134: 32.88
+	Rn
		250479 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KCC1B_RAT (8-290): 3.73e-28: 119: 28.97
+	Mm
		250791 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		ULK1_MOUSE (10-247): 6.62e-25: 114: 29.41
+	Hs
		116959 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		SGK1_HUMAN (3-269): 2.09e-25: 112: 29.56
+	Hs
		262227 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		ULK1_HUMAN (10-247): 4.69e-24: 112: 28.63
+	Sc
		477597 RL40A_YEAST (1-72): 1.75e-29: 106: 41.67		RAD53_YEAST (5-287): 2.59e-24: 112: 29.87