HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: SGTB (Q96EQ0)
Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)
Gene: SGTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	26496610, 32296183, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	SGTA_dimer~ubiquitin
Common GO terms	GO:0006620 - post-translational protein targeting to endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 304
+	Hs
		213469 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		SGTA_HUMAN (1-303): 5.48e-58: 190: 57.56
+	Rn
		1144228 UBC_RAT (1-102): 9.46e-29: 112: 31.13		SGTB_RAT (1-304): 7.75e-67: 212: 96.05
+	Hs
		213522 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		SGTA_HUMAN (1-303): 5.48e-58: 190: 57.56
+	Hs
		213459 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		SGTA_HUMAN (1-303): 5.48e-58: 190: 57.56
+	Rn
		251113 UBC_RAT (1-102): 9.46e-29: 112: 31.13		SGTA_RAT (1-303): 4.06e-56: 185: 56.09
+	Hs
		213523 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		SGTA_HUMAN (1-303): 5.48e-58: 190: 57.56
+	Mm
		924235 RS27A_MOUSE (1-123): 2.97e-40: 134: 28.46		PPP5_MOUSE (64-239): 1.31e-38: 143: 24.86
+	Hs
		476568 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		CHIP_HUMAN (63-222): 5.78e-40: 143: 26.67
+	Hs
		924436 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		CHIP_HUMAN (63-222): 5.78e-40: 143: 26.67
+	Hs
		174581 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		OGT1_HUMAN (79-288): 8e-22: 97.6: 13.33
+	Mm
		56866 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		CDC27_MOUSE (6-239): 4.45e-27: 112: 15.39
+	Hs
		475381 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		CDC27_HUMAN (6-239): 5.08e-27: 112: 15.39
+	Rn
		881491 UBC_RAT (1-102): 9.46e-29: 112: 31.13		OGT1_RAT (81-288): 9.91e-22: 97.6: 13.94
+	Hs
		174570 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		OGT1_HUMAN (79-288): 8e-22: 97.6: 13.33
+	Rn
		193485 UBC_RAT (1-102): 9.46e-29: 112: 31.13		STIP1_RAT (69-291): 1.62e-16: 81.7: 17.60
+	At
		886694 R27AC_ARATH (1-72): 1.05e-31: 112: 40.28		CHIP_ARATH (85-182): 6.75e-17: 80.9: 42.86
+	Sc
		477102 UBI4P_YEAST (1-76): 6.18e-27: 105: 39.47		STI1_YEAST (48-210): 1.27e-17: 84.8: 23.53
+	At
		1114641 RL40B_ARATH (1-72): 4.49e-29: 105: 40.28		CHIP_ARATH (85-182): 6.75e-17: 80.9: 42.86
+	Pf
		1181548 Q7KQK2_PLAF7 (1-76): 2.64e-28: 109: 39.47		HSOP_PLAF7 (53-289): 7.7e-14: 73.7: 12.96