HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: RN185 (Q96GF1)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: RNF185

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17558393
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Hs			1 192
+	Hs
		924117 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		RN185_HUMAN (1-192): 2.35e-56: 178: 100.00
+	Xl
		1140130 Q6GMC1_XENLA (1-123): 2.9e-40: 134: 28.46		Q5XGX4_XENLA (1-192): 1.06e-55: 176: 91.15
+	Mm
		476948 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		RN185_MOUSE (1-192): 3.58e-60: 187: 98.44
+	Hs
		475137 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		RN185_HUMAN (1-192): 2.35e-56: 178: 100.00
+	Hs
		476198 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RN185_HUMAN (1-192): 2.35e-56: 178: 100.00
+	Mm
		924236 RS27A_MOUSE (1-123): 2.97e-40: 134: 28.46		RO52_MOUSE (21-142): 6.24e-28: 110: 16.39
+	Hs
		509744 UBL4A_HUMAN (1-157): 6.07e-43: 141: 100.00		AMFR_HUMAN (27-171): 2.12e-24: 101: 19.18
+	Hs
		476274 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RNF5_HUMAN (15-173): 2.18e-37: 129: 60.38
+	Hs
		924212 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		AMFR_HUMAN (27-171): 2.12e-24: 101: 19.18
+	Dm
		547968 RS27A_DROME (1-123): 4.88e-39: 131: 28.46		Q9W3I9_DROME (6-78): 2.87e-21: 92.2: 34.25
+	Mm
		476831 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		RO52_MOUSE (21-142): 6.24e-28: 110: 16.39
+	Mm
		476671 UBB_MOUSE (1-76): 9.53e-29: 109: 39.47		RO52_MOUSE (21-142): 6.24e-28: 110: 16.39
+	Hs
		475680 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		TRI26_HUMAN (26-132): 1.42e-27: 109: 23.48
+	Hs
		475134 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		TRI11_HUMAN (27-130): 9.09e-27: 107: 25.00
+	Hs
		475328 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RO52_HUMAN (26-144): 2e-26: 106: 20.17
+	Hs
		476418 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		TRI39_HUMAN (12-144): 3.88e-26: 106: 18.80
+	Hs
		475759 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		HLTF_HUMAN (1-129): 3.34e-24: 101: 20.93
+	Hs
		476551 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		AMFR_HUMAN (27-171): 2.12e-24: 101: 19.18
+	Hs
		474945 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		BRCA1_HUMAN (38-88): 2.19e-11: 64: 35.29
+	Hs
		475431 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		BRCA1_HUMAN (38-88): 2.19e-11: 64: 35.29