HitPredict

Interactor 1: ERR1 (P11474)
Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1)
Gene: ESRRA

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 Hs			1 526
+	Hs
		587128 RXRA_HUMAN (1-420): 2.08e-125: 372: 29.37		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		370139 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10
+	Hs
		369097 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		611479 NR4A1_HUMAN (3-422): 2.87e-104: 322: 29.95		RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10
+	Hs
		369431 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Mm
		509294 RARA_MOUSE (8-419): 5.95e-111: 335: 25.00		FUS_MOUSE (1-526): 6.91e-34: 136: 86.72
+	Hs
		370711 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Mm
		1142642 ERR2_MOUSE (3-422): 1.83e-112: 338: 54.46		EWS_MOUSE (3-451): 2.8e-30: 127: 35.56
+	Mm
		509319 RARA_MOUSE (8-419): 5.95e-111: 335: 25.00		EWS_MOUSE (3-451): 2.8e-30: 127: 35.56
+	Hs
		370820 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35
+	Hs
		377835 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35
+	Hs
		369739 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PAP1L_HUMAN (182-382): 2.39e-13: 74.7: 13.43
+	Hs
		369534 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		212165 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30
+	Hs
		368886 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		782537 HNF4A_HUMAN (29-418): 1.51e-110: 335: 26.09		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		370422 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05
+	Mm
		509289 RARA_MOUSE (8-419): 5.95e-111: 335: 25.00		PABP1_MOUSE (184-382): 3.6e-12: 70.8: 12.44
+	Hs
		611434 NR4A1_HUMAN (3-422): 2.87e-104: 322: 29.95		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		516359 NR4A1_HUMAN (3-422): 2.87e-104: 322: 29.95		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44