HitPredict

Interactor 1: ERR1 (P11474)
Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1)
Gene: ESRRA

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 Hs			1 7388
+	Hs
		370715 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		MACF1_HUMAN (1-7388): 0: 2387: 100.00
+	Hs
		369273 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		368926 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		369641 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		885285 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		377068 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		551794 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		370043 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		369446 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		513834 HNF4A_HUMAN (29-418): 1.51e-110: 335: 26.09		DMD_HUMAN (239-1700): 1.65e-14: 84.4: 8.22
+	Hs
		369420 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		369158 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		320227 ERR2_HUMAN (3-422): 1.9e-116: 348: 56.10		SPTN4_HUMAN (4289-5023): 8.23e-09: 65.5: 19.24
+	Hs
		368893 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		369619 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		369568 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		521532 NR1H3_HUMAN (2-417): 1.47e-105: 321: 24.59		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		164649 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		809148 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		521591 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07