HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: MAS5 (P25491)
Mitochondrial protein import protein MAS5 (Yeast dnaJ protein 1)
Gene: YDJ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	8144572, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042026 - protein refolding and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Sc			1 409
+	Sc
		633263 SSB2_YEAST (1-613): 0: 1118: 99.35		MAS5_YEAST (1-409): 1.76e-161: 461: 100.00
+	Sc
		512293 SSB1_YEAST (1-613): 0: 1128: 100.00		APJ1_YEAST (1-353): 1.92e-68: 227: 35.19
+	Hs
		564015 HSP76_HUMAN (3-612): 0: 901: 58.66		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		503527 HSP7C_HUMAN (5-612): 0: 900: 59.84		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		483775 HS71B_HUMAN (5-611): 0: 897: 59.93		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		564136 HSP76_HUMAN (3-612): 0: 901: 58.66		DNJA4_HUMAN (1-408): 3.64e-148: 427: 46.10
+	Hs
		681341 HS71L_HUMAN (5-612): 0: 896: 59.34		DNJA1_HUMAN (1-408): 2.99e-150: 432: 45.61
+	Hs
		243284 HSP76_HUMAN (3-612): 0: 901: 58.66		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Hs
		243275 HSP7C_HUMAN (5-612): 0: 900: 59.84		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Hs
		243312 HS71L_HUMAN (5-612): 0: 896: 59.34		DNJA2_HUMAN (2-409): 1.74e-143: 416: 45.39
+	Sc
		511344 SSB1_YEAST (1-613): 0: 1128: 100.00		XDJ1_YEAST (6-354): 3.48e-46: 166: 34.54
+	Hs
		279274 HSP76_HUMAN (3-612): 0: 901: 58.66		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		279272 HSP7C_HUMAN (5-612): 0: 900: 59.84		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		564203 HSP76_HUMAN (3-612): 0: 901: 58.66		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Hs
		504564 HSP7C_HUMAN (5-612): 0: 900: 59.84		DNJA3_HUMAN (2-398): 1.93e-117: 352: 25.00
+	Hs
		504901 HSP7C_HUMAN (5-612): 0: 900: 59.84		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Hs
		279280 HS71L_HUMAN (5-612): 0: 896: 59.34		DNJB5_HUMAN (5-354): 1.05e-119: 353: 33.05
+	Hs
		483809 HS71B_HUMAN (5-611): 0: 897: 59.93		DNJB4_HUMAN (5-356): 2.73e-119: 352: 31.76
+	Hs
		564202 HSP76_HUMAN (3-612): 0: 901: 58.66		DJB11_HUMAN (7-349): 1.79e-48: 170: 36.60
+	Hs
		504897 HSP7C_HUMAN (5-612): 0: 900: 59.84		DJB11_HUMAN (7-349): 1.79e-48: 170: 36.60