HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: SP110 (P32380)
Spindle pole body component 110 (Extragenic suppressor of CMD1-1 mutant protein 1) (Nuclear filament-related protein 1) (Spindle pole body spacer protein SPC110)
Gene: SPC110

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	9585415, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 944
+	Sc
		510394 SSB1_YEAST (1-613): 0: 1128: 100.00		USO1_YEAST (381-881): 3.87e-15: 82.5: 13.57
+	Sc
		630960 SSB2_YEAST (1-613): 0: 1118: 99.35		USO1_YEAST (381-881): 3.87e-15: 82.5: 13.57
+	Hs
		504493 HSP7C_HUMAN (5-612): 0: 900: 59.84		MY18A_HUMAN (50-754): 2.91e-27: 122: 14.14
+	Hs
		503376 HSP7C_HUMAN (5-612): 0: 900: 59.84		DESP_HUMAN (118-831): 3.31e-14: 79.6: 11.69
+	Hs
		254440 HSP7C_HUMAN (5-612): 0: 900: 59.84		ROCK2_HUMAN (341-817): 1.11e-13: 77.7: 13.74
+	Hs
		148367 HSP76_HUMAN (3-612): 0: 901: 58.66		CTRO_HUMAN (119-722): 1.75e-10: 67.4: 20.65
+	Hs
		148327 HSP7C_HUMAN (5-612): 0: 900: 59.84		CTRO_HUMAN (119-722): 1.75e-10: 67.4: 20.65
+	Hs
		64578 HSP7C_HUMAN (5-612): 0: 900: 59.84		MYH7B_HUMAN (563-936): 8.73e-10: 65: 10.82
+	Hs
		148449 HS71L_HUMAN (5-612): 0: 896: 59.34		CTRO_HUMAN (119-722): 1.75e-10: 67.4: 20.65
+	Hs
		148576 HSP72_HUMAN (4-612): 0: 891: 59.97		CTRO_HUMAN (119-722): 1.75e-10: 67.4: 20.65
+	Sc
		449957 HSP73_YEAST (9-611): 0: 677: 60.66		SP110_YEAST (1-944): 2.68e-70: 253: 100.00