HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22940862, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 2672
+	Sc
		707866 SSB2_YEAST (1-613): 0: 1118: 99.35		GCN1_YEAST (1-2672): 0: 1798: 100.00
+	Sc
		449999 HSP73_YEAST (9-611): 0: 677: 60.66		GCN1_YEAST (1-2672): 0: 1798: 100.00
+	Sc
		510156 SSB1_YEAST (1-613): 0: 1128: 100.00		EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87
+	Sc
		512313 SSB1_YEAST (1-613): 0: 1128: 100.00		EF3B_YEAST (1321-1674): 3.58e-82: 297: 22.69
+	Sc
		560987 SSB2_YEAST (1-613): 0: 1118: 99.35		EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87
+	Sc
		513063 SSB1_YEAST (1-613): 0: 1128: 100.00		NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95
+	Sc
		769709 SSB2_YEAST (1-613): 0: 1118: 99.35		NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95
+	Sc
		510842 SSB1_YEAST (1-613): 0: 1128: 100.00		UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49
+	Sc
		715932 SSB2_YEAST (1-613): 0: 1118: 99.35		UTP20_YEAST (1367-2411): 3.05e-15: 85.2: 11.49
+	Hs
		503510 HSP7C_HUMAN (5-612): 0: 900: 59.84		2AAA_HUMAN (1315-1936): 3.9e-70: 250: 14.42
+	Hs
		503511 HSP7C_HUMAN (5-612): 0: 900: 59.84		2AAB_HUMAN (1663-2209): 4.74e-57: 212: 14.98
+	Sp
		223785 HSP72_SCHPO (6-612): 0: 874: 59.44		2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92
+	Hs
		504227 HSP7C_HUMAN (5-612): 0: 900: 59.84		ECM29_HUMAN (1400-2598): 3.58e-14: 81.2: 10.27
+	Hs
		504341 HSP7C_HUMAN (5-612): 0: 900: 59.84		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Hs
		714005 HS71L_HUMAN (5-612): 0: 896: 59.34		CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54
+	Dm
		505106 HSP7D_DROME (5-612): 0: 884: 58.85		Q9VRV9_DROME (757-1454): 1.82e-11: 72.1: 9.86
+	Sp
		1013730 SSB1_SCHPO (5-612): 0: 782: 69.79		2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92