HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: TSA1 (P34760)
Peroxiredoxin TSA1 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 1) (cTPx 1) (Protector protein) (PRP) (Thiol-specific antioxidant protein 1) (Thioredoxin peroxidase type Ia) (TPx type Ia) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin TSA1)
Gene: TSA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27634403, 22940862
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051082 - unfolded protein binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 196
+	Sc
		713231 SSB2_YEAST (1-613): 0: 1118: 99.35		TSA1_YEAST (1-196): 3.79e-93: 271: 100.00
+	Sc
		512602 SSB1_YEAST (1-613): 0: 1128: 100.00		TSA2_YEAST (1-195): 2.04e-88: 259: 86.15
+	Sc
		510814 SSB1_YEAST (1-613): 0: 1128: 100.00		PRX1_YEAST (3-196): 8.29e-70: 214: 28.16
+	Sc
		710638 SSB2_YEAST (1-613): 0: 1118: 99.35		PRX1_YEAST (3-196): 8.29e-70: 214: 28.16
+	Hs
		503536 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRDX2_HUMAN (4-195): 1.42e-104: 300: 66.67
+	Hs
		503953 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRDX1_HUMAN (4-193): 5.55e-100: 289: 59.69
+	Hs
		504009 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRDX4_HUMAN (4-195): 2.66e-97: 284: 55.21
+	Hs
		503505 HSP7C_HUMAN (5-612): 0: 900: 59.84		PRDX6_HUMAN (3-193): 4.87e-68: 209: 25.00
+	Sc
		605327 HSP74_YEAST (9-611): 0: 681: 62.15		TSA1_YEAST (1-196): 3.79e-93: 271: 100.00