HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: TCPB (P39076)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta)
Gene: CCT2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0051082 - unfolded protein binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 527
+	Sc
		760623 SSB2_YEAST (1-613): 0: 1118: 99.35		TCPB_YEAST (1-527): 0: 553: 100.00
+	Sc
		511717 SSB1_YEAST (1-613): 0: 1128: 100.00		TCPH_YEAST (3-527): 0: 537: 32.26
+	Sc
		511338 SSB1_YEAST (1-613): 0: 1128: 100.00		TCPG_YEAST (2-522): 0: 527: 27.05
+	Sc
		768715 SSB2_YEAST (1-613): 0: 1118: 99.35		TCPH_YEAST (3-527): 0: 537: 32.26
+	Sc
		760741 SSB2_YEAST (1-613): 0: 1118: 99.35		TCPG_YEAST (2-522): 0: 527: 27.05
+	Hs
		504643 HSP7C_HUMAN (5-612): 0: 900: 59.84		TCPH_HUMAN (2-517): 0: 570: 34.36
+	Hs
		503673 HSP7C_HUMAN (5-612): 0: 900: 59.84		TCPG_HUMAN (2-525): 0: 552: 27.15
+	Hs
		503881 HSP7C_HUMAN (5-612): 0: 900: 59.84		TCPB_HUMAN (2-526): 0: 544: 65.59
+	Hs
		503400 HSP7C_HUMAN (5-612): 0: 900: 59.84		TCPA_HUMAN (10-526): 0: 527: 33.02
+	Hs
		503661 HSP7C_HUMAN (5-612): 0: 900: 59.84		TCPE_HUMAN (2-514): 0: 526: 33.65
+	Sc
		511552 SSB1_YEAST (1-613): 0: 1128: 100.00		TCPE_YEAST (5-515): 1.24e-77: 256: 35.09
+	Sc
		768587 SSB2_YEAST (1-613): 0: 1118: 99.35		TCPE_YEAST (5-515): 1.24e-77: 256: 35.09
+	Sc
		605350 HSP74_YEAST (9-611): 0: 681: 62.15		TCPB_YEAST (1-527): 0: 553: 100.00
+	Sc
		450051 HSP73_YEAST (9-611): 0: 677: 60.66		TCPB_YEAST (1-527): 0: 553: 100.00
+	Sc
		450083 HSP73_YEAST (9-611): 0: 677: 60.66		TCPH_YEAST (3-527): 0: 537: 32.26