HitPredict

Interactor 1: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Interactor 2: IMB4 (P40069)
Importin subunit beta-4 (Importin-123) (Karyopherin subunit beta-4) (Karyopherin-123) (Ran-binding protein YRB4)
Gene: KAP123

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	21482668, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 613 Sc			1 1113
+	Sc
		767647 SSB2_YEAST (1-613): 0: 1118: 99.35		IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00
+	Sc
		510571 SSB1_YEAST (1-613): 0: 1128: 100.00		IMB3_YEAST (5-1065): 1.11e-110: 372: 17.51
+	Hs
		504459 HSP7C_HUMAN (5-612): 0: 900: 59.84		IPO4_HUMAN (19-1096): 2.49e-116: 388: 20.18
+	Sc
		512784 SSB1_YEAST (1-613): 0: 1128: 100.00		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Sc
		769512 SSB2_YEAST (1-613): 0: 1118: 99.35		IMB1_YEAST (6-696): 1.11e-36: 151: 13.31
+	Sc
		605354 HSP74_YEAST (9-611): 0: 681: 62.15		IMB4_YEAST (1-1113): 2.41e-177: 551: 100.00
+	Hs
		504341 HSP7C_HUMAN (5-612): 0: 900: 59.84		CAND1_HUMAN (1-1112): 1.78e-93: 327: 11.03
+	Hs
		714005 HS71L_HUMAN (5-612): 0: 896: 59.34		CAND1_HUMAN (1-1112): 1.78e-93: 327: 11.03
+	Dm
		505106 HSP7D_DROME (5-612): 0: 884: 58.85		Q9VRV9_DROME (257-1056): 1.22e-76: 272: 12.37
+	Hs
		504100 HSP7C_HUMAN (5-612): 0: 900: 59.84		IMB1_HUMAN (336-1075): 4.67e-46: 181: 11.11